Endocrine Abstracts

Background Insulin resistance (IR) is a state in which a given concentration of insulin produces biological effect less than expected and IR actually make up a broad clinical spectrum, including obesity, glucose intolerance, DM, and the metabolic syndrome that are associated with various endocrine, metabolic, & genetic conditions. There is an association of IR with thyroid abnormalities. Evidence for a relationship between T4 and T3 and glucose metabolism appeared over 100...

Back ground and objectives: Relation between thyroid function with respect to insulin resistance has been a field that is rich and captivating for research and further examination. Few studies have suggested that metformin, the first-line in diabetes management, may lower thyroid-stimu-lating hormone (TSH). Owing to Paucity of studies regarding the effect of metformin on TSH in hypothyroidism patients, this study compares the effect of metformin on TSH and BMI in Egyptian na&#...

IntroductionRecent studies in patients with Addison’s disease have shown that this condition, even if treated, is fraught with significant morbidity and even excess mortality. The objective of our study was to determine the deleterious effects of long-term glucocorticoid replacement mainly on the metabolic level.MethodsRetrospective study, carried out at the Endocrinology and Diabetology Department of H&...